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SGK1 Rabbit mAb
商品貨號(hào): PRM8879
適 應(yīng) 性: 人,小鼠,大鼠
WB IHC IF ELISA IP
¥800元
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說(shuō)明書(shū)
商品描述
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點(diǎn)-Target: SGK1
  • 反應(yīng)性-Reactivity: 人,小鼠,大鼠
  • 應(yīng)用-Applications: WB,IHC,IF,IP,ELISA
  • MW(Calculated): 49kD
  • MW(Observed): 49kD
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG,Kappa
  • 偶聯(lián)-Conjugate: Unmodified
  • 推薦稀釋比: IHC 1:200-1:1000;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性: Monoclonal
  • 克隆號(hào): PT1163R
  • 特異性: Endogenous
  • 基因名稱(chēng): SGK1
  • 蛋白名稱(chēng): Serine/threonine-protein kinase Sgk1
  • 別名: SGK1;SGK;Serine/threonine-protein kinase Sgk1;Serum/glucocorticoid-regulated kinase 1
  • Organism-1: Human
  • 基因ID-1: 6446
  • SwissProt-1: O00141
  • Organism-2: Mouse
  • 基因ID-2: 20393
  • SwissProt-2: Q9WVC6
  • Organism-3: Rat
  • SwissProt-3: Q06226
  • 背景: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009],
  • 細(xì)胞定位: Cytoplasm. Nucleus. Endoplasmic reticulum membrane. Cell membrane. Mitochondrion. The subcellular localization is controlled by the cell cycle, as well as by exposure to specific hormones and environmental stress stimuli. In proliferating cells, it shuttles between the nucleus and cytoplasm in synchrony with the cell cycle, and in serum/growth factor-stimulated cells it resides in the nucleus. In contrast, after exposure to environmental stress or treatment with glucocorticoids, it is detected in the cytoplasm and with certain stress conditions is associated with the mitochondria. In osmoregulation through the epithelial sodium channel, it can be localized to the cytoplasmic surface of the cell membrane. Nuclear, upon phosphorylation.; [Isoform 2]: Cell membrane.
SGK1 Rabbit mAb
Catalog No PRM8879
Product information
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點(diǎn)-Target: SGK1
  • 反應(yīng)性-Reactivity: 人,小鼠,大鼠
  • 應(yīng)用-Applications: WB,IHC,IF,IP,ELISA
  • MW(Calculated): 49kD
  • MW(Observed): 49kD
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG,Kappa
  • 偶聯(lián)-Conjugate: Unmodified
  • 推薦稀釋比: IHC 1:200-1:1000;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性: Monoclonal
  • 克隆號(hào): PT1163R
  • 特異性: Endogenous
  • 基因名稱(chēng): SGK1
  • 蛋白名稱(chēng): Serine/threonine-protein kinase Sgk1
  • 別名: SGK1;SGK;Serine/threonine-protein kinase Sgk1;Serum/glucocorticoid-regulated kinase 1
  • Organism-1: Human
  • 基因ID-1: 6446
  • SwissProt-1: O00141
  • Organism-2: Mouse
  • 基因ID-2: 20393
  • SwissProt-2: Q9WVC6
  • Organism-3: Rat
  • SwissProt-3: Q06226
  • 背景: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009],
  • 細(xì)胞定位: Cytoplasm. Nucleus. Endoplasmic reticulum membrane. Cell membrane. Mitochondrion. The subcellular localization is controlled by the cell cycle, as well as by exposure to specific hormones and environmental stress stimuli. In proliferating cells, it shuttles between the nucleus and cytoplasm in synchrony with the cell cycle, and in serum/growth factor-stimulated cells it resides in the nucleus. In contrast, after exposure to environmental stress or treatment with glucocorticoids, it is detected in the cytoplasm and with certain stress conditions is associated with the mitochondria. In osmoregulation through the epithelial sodium channel, it can be localized to the cytoplasmic surface of the cell membrane. Nuclear, upon phosphorylation.; [Isoform 2]: Cell membrane.
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.hyjdss.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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