儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT1039R
特異性： Endogenous
基因名稱： G3BP1 G3BP
蛋白名稱： Ras GTPase-activating protein-binding protein 1
別名： G3BP1;G3BP;Ras GTPase-activating protein-binding protein 1;G3BP-1;ATP-dependent DNA helicase VIII;hDH VIII;GAP SH3 domain-binding protein 1
Organism-1： Human
基因ID-1： 10146
SwissProt-1： Q13283
Organism-2： Mouse
基因ID-2： 27041
SwissProt-2： P97855
背景： This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],
細胞定位： Cytoplasm, cytosol . Perikaryon . Cytoplasm, Stress granule . Nucleus . Cytoplasmic in proliferating cells (PubMed:11604510). Cytosolic and partially nuclear in resting cells (PubMed:11604510). Recruited to stress granules in response to arsenite treatment (PubMed:12642610, PubMed:20180778). The unphosphorylated form is recruited to stress granules (PubMed:12642610). HRAS signaling contributes to this process by regulating G3BP dephosphorylation (PubMed:12642610). .
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT1039R
特異性： Endogenous
基因名稱： G3BP1 G3BP
蛋白名稱： Ras GTPase-activating protein-binding protein 1
別名： G3BP1;G3BP;Ras GTPase-activating protein-binding protein 1;G3BP-1;ATP-dependent DNA helicase VIII;hDH VIII;GAP SH3 domain-binding protein 1
Organism-1： Human
基因ID-1： 10146
SwissProt-1： Q13283
Organism-2： Mouse
基因ID-2： 27041
SwissProt-2： P97855
背景： This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],
細胞定位： Cytoplasm, cytosol . Perikaryon . Cytoplasm, Stress granule . Nucleus . Cytoplasmic in proliferating cells (PubMed:11604510). Cytosolic and partially nuclear in resting cells (PubMed:11604510). Recruited to stress granules in response to arsenite treatment (PubMed:12642610, PubMed:20180778). The unphosphorylated form is recruited to stress granules (PubMed:12642610). HRAS signaling contributes to this process by regulating G3BP dephosphorylation (PubMed:12642610). .
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