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首頁(yè) > 抗體 > 兔單抗 > Nogo B receptor (PT1129R) PT® Rabbit mAb
Nogo B receptor (PT1129R) PT® Rabbit mAb
商品貨號(hào): PRM8779
適 應(yīng) 性: Human,Mouse,Rat
WB
¥800元
規(guī)格:
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MSDS
說(shuō)明書(shū)
商品描述
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點(diǎn)-Target: Nogo B receptor
  • 反應(yīng)性-Reactivity: Human,Mouse,Rat
  • 應(yīng)用-Applications: WB
  • MW(Calculated): 32kDa
  • MW(Observed): 32kDa
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG,Kappa
  • 偶聯(lián)-Conjugate: Unmodified
  • 推薦稀釋比: WB 1:1000-1:5000;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號(hào): PT1129R
  • 特異性: Endogenous
  • 基因名稱: NUS1,C6orf68,NGBR
  • 蛋白名稱: Dehydrodolichyl diphosphate synthase complex subunit NUS1 (EC 2.5.1.87) (Cis-prenyltransferase subunit NgBR) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog)
  • 別名: C6orf68 NGBR
  • Organism-1: Human
  • 基因ID-1: 116150
  • SwissProt-1: Q96E22
  • Organism-2: Mouse
  • 基因ID-2: 52014
  • SwissProt-2: Q99LJ8
  • 背景: This gene encodes a type I single transmembrane domain receptor, which is a subunit of cis-prenyltransferase, and serves as a specific receptor for the neural and cardiovascular regulator Nogo-B. The encoded protein is essential for dolichol synthesis and protein glycosylation. This gene is highly expressed in non-small cell lung carcinomas as well as estrogen receptor-alpha positive breast cancer cells where it promotes epithelial mesenchymal transition. This gene is associated with the poor prognosis of human hepatocellular carcinoma patients. Naturally occurring mutations in this gene cause a congenital disorder of glycosylation and are associated with epilepsy. A knockout of the orthologous gene in mice causes embryonic lethality before day 6.5. Pseudogenes of this gene have been defined on chromosomes 13 and X. [provided by RefSeq, May 2017]
  • 細(xì)胞定位: SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19723497, ECO:0000269|PubMed:21572394}; Multi-pass membrane protein {ECO:0000303|PubMed:21572394}. Note=Colocalizes with Nogo-B during VEGF and wound healing angiogenesis. {ECO:0000269|PubMed:19723497}.
Nogo B receptor (PT1129R) PT® Rabbit mAb
Catalog No PRM8779
Product information
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點(diǎn)-Target: Nogo B receptor
  • 反應(yīng)性-Reactivity: Human,Mouse,Rat
  • 應(yīng)用-Applications: WB
  • MW(Calculated): 32kDa
  • MW(Observed): 32kDa
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG,Kappa
  • 偶聯(lián)-Conjugate: Unmodified
  • 推薦稀釋比: WB 1:1000-1:5000;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號(hào): PT1129R
  • 特異性: Endogenous
  • 基因名稱: NUS1,C6orf68,NGBR
  • 蛋白名稱: Dehydrodolichyl diphosphate synthase complex subunit NUS1 (EC 2.5.1.87) (Cis-prenyltransferase subunit NgBR) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog)
  • 別名: C6orf68 NGBR
  • Organism-1: Human
  • 基因ID-1: 116150
  • SwissProt-1: Q96E22
  • Organism-2: Mouse
  • 基因ID-2: 52014
  • SwissProt-2: Q99LJ8
  • 背景: This gene encodes a type I single transmembrane domain receptor, which is a subunit of cis-prenyltransferase, and serves as a specific receptor for the neural and cardiovascular regulator Nogo-B. The encoded protein is essential for dolichol synthesis and protein glycosylation. This gene is highly expressed in non-small cell lung carcinomas as well as estrogen receptor-alpha positive breast cancer cells where it promotes epithelial mesenchymal transition. This gene is associated with the poor prognosis of human hepatocellular carcinoma patients. Naturally occurring mutations in this gene cause a congenital disorder of glycosylation and are associated with epilepsy. A knockout of the orthologous gene in mice causes embryonic lethality before day 6.5. Pseudogenes of this gene have been defined on chromosomes 13 and X. [provided by RefSeq, May 2017]
  • 細(xì)胞定位: SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19723497, ECO:0000269|PubMed:21572394}; Multi-pass membrane protein {ECO:0000303|PubMed:21572394}. Note=Colocalizes with Nogo-B during VEGF and wound healing angiogenesis. {ECO:0000269|PubMed:19723497}.
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.hyjdss.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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