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首頁 > 抗體 > 兔單抗 > SH-PTP1 Rabbit mAb
SH-PTP1 Rabbit mAb
商品貨號: PRM8728
適 應(yīng) 性: 人,小鼠,大鼠
WB IHC IF ELISA IP
¥800元
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商品描述
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點-Target: SH-PTP1
  • 反應(yīng)性-Reactivity: 人,小鼠,大鼠
  • 應(yīng)用-Applications: WB,IHC,IF,IP,ELISA
  • MW(Calculated): 68kD
  • MW(Observed): 68kD
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG, Kappa
  • 偶聯(lián)-Conjugate: Unmodified
  • 推薦稀釋比: IHC 1:500-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號: PT1030R
  • 特異性: Endogenous
  • 基因名稱: PTPN6
  • 蛋白名稱: Tyrosine-protein phosphatase non-receptor type 6
  • 別名: PTPN6;HCP;PTP1C;Tyrosine-protein phosphatase non-receptor type 6;Hematopoietic cell protein-tyrosine phosphatase;Protein-tyrosine phosphatase 1C;PTP-1C;Protein-tyrosine phosphatase SHP-1;SH-PTP1
  • Organism-1: Human
  • 基因ID-1: 5777
  • SwissProt-1: P29350
  • Organism-2: Mouse
  • 基因ID-2: 15170
  • SwissProt-2: P29351
  • Organism-3: Rat
  • 基因ID-3: 116689
  • SwissProt-3: P81718
  • 背景: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul
  • 細胞定位: Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity). Shuttles between the cytoplasm and nucleus via its association with PDPK1. .
SH-PTP1 Rabbit mAb
Catalog No PRM8728
Product information
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點-Target: SH-PTP1
  • 反應(yīng)性-Reactivity: 人,小鼠,大鼠
  • 應(yīng)用-Applications: WB,IHC,IF,IP,ELISA
  • MW(Calculated): 68kD
  • MW(Observed): 68kD
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG, Kappa
  • 偶聯(lián)-Conjugate: Unmodified
  • 推薦稀釋比: IHC 1:500-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號: PT1030R
  • 特異性: Endogenous
  • 基因名稱: PTPN6
  • 蛋白名稱: Tyrosine-protein phosphatase non-receptor type 6
  • 別名: PTPN6;HCP;PTP1C;Tyrosine-protein phosphatase non-receptor type 6;Hematopoietic cell protein-tyrosine phosphatase;Protein-tyrosine phosphatase 1C;PTP-1C;Protein-tyrosine phosphatase SHP-1;SH-PTP1
  • Organism-1: Human
  • 基因ID-1: 5777
  • SwissProt-1: P29350
  • Organism-2: Mouse
  • 基因ID-2: 15170
  • SwissProt-2: P29351
  • Organism-3: Rat
  • 基因ID-3: 116689
  • SwissProt-3: P81718
  • 背景: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul
  • 細胞定位: Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity). Shuttles between the cytoplasm and nucleus via its association with PDPK1. .
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.hyjdss.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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