儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號： PT0950R
特異性： Endogenous
基因名稱： CUL4A/CUL4B
蛋白名稱： Cullin-4A (CUL-4A)/Cullin-4B
別名： CUL4B;KIAA0695;Cullin-4B;CUL-4B
Organism-1： Human
基因ID-1： 8451;8450
SwissProt-1： Q13619;Q13620
Organism-2： Mouse
SwissProt-2： Q3TCH7,A2A432
背景： CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]).[supplied by OMIM, Oct 2009],CUL4B is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號： PT0950R
特異性： Endogenous
基因名稱： CUL4A/CUL4B
蛋白名稱： Cullin-4A (CUL-4A)/Cullin-4B
別名： CUL4B;KIAA0695;Cullin-4B;CUL-4B
Organism-1： Human
基因ID-1： 8451;8450
SwissProt-1： Q13619;Q13620
Organism-2： Mouse
SwissProt-2： Q3TCH7,A2A432
背景： CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]).[supplied by OMIM, Oct 2009],CUL4B is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
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