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首頁 > 抗體 > 兔單抗 > IRF3 (Phospho Ser386) Rabbit mAb
IRF3 (Phospho Ser386) Rabbit mAb
商品貨號: PRM8640
適 應(yīng) 性: 人,
WB IF ELISA IP
¥7000元
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商品描述
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點-Target: IRF-3
  • 反應(yīng)性-Reactivity: 人,
  • 應(yīng)用-Applications: WB,IF,IP,ELISA
  • MW(Calculated): 47kD
  • MW(Observed): 60kD
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG, Kappa
  • 偶聯(lián)-Conjugate: Phospho
  • 修飾-Modification: Ser386
  • 推薦稀釋比: WB 1:1000-1:15000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號: PT0984R
  • 特異性: IRF3 (Phospho Ser386) Monoclonal Antibody detects endogenous levels of IRF-3 protein only when phosphorylated at S386.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ASsLE
  • 基因名稱: IRF3
  • 蛋白名稱: Interferon regulatory factor 3
  • 別名: IRF3;Interferon regulatory factor 3;IRF-3
  • Organism-1: Human
  • 基因ID-1: 3661
  • SwissProt-1: Q14653
  • Organism-2: Mouse
  • SwissProt-2: P70671
  • 背景: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
  • 細胞定位: Cytoplasm . Nucleus . Mitochondrion . Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect (PubMed:10805757). When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm (PubMed:10805757). Recruited to mitochondria via TOMM70:HSP90AA1 upon Sendai virus infection (PubMed:25609812). .
IRF3 (Phospho Ser386) Rabbit mAb
Catalog No PRM8640
Product information
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點-Target: IRF-3
  • 反應(yīng)性-Reactivity: 人,
  • 應(yīng)用-Applications: WB,IF,IP,ELISA
  • MW(Calculated): 47kD
  • MW(Observed): 60kD
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG, Kappa
  • 偶聯(lián)-Conjugate: Phospho
  • 修飾-Modification: Ser386
  • 推薦稀釋比: WB 1:1000-1:15000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號: PT0984R
  • 特異性: IRF3 (Phospho Ser386) Monoclonal Antibody detects endogenous levels of IRF-3 protein only when phosphorylated at S386.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ASsLE
  • 基因名稱: IRF3
  • 蛋白名稱: Interferon regulatory factor 3
  • 別名: IRF3;Interferon regulatory factor 3;IRF-3
  • Organism-1: Human
  • 基因ID-1: 3661
  • SwissProt-1: Q14653
  • Organism-2: Mouse
  • SwissProt-2: P70671
  • 背景: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
  • 細胞定位: Cytoplasm . Nucleus . Mitochondrion . Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect (PubMed:10805757). When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm (PubMed:10805757). Recruited to mitochondria via TOMM70:HSP90AA1 upon Sendai virus infection (PubMed:25609812). .
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.hyjdss.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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