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Smad1 Rabbit mAb
商品貨號(hào): PRM8634
適 應(yīng) 性: 人,小鼠,大鼠
WB IF ELISA IP
¥800元
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MSDS
說(shuō)明書
商品描述
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點(diǎn)-Target: Smad1
  • 反應(yīng)性-Reactivity: 人,小鼠,大鼠
  • 應(yīng)用-Applications: WB,IF,IP,ELISA
  • MW(Calculated): 52kD
  • MW(Observed): 52kD
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG,Kappa
  • 偶聯(lián)-Conjugate: Unmodified
  • 推薦稀釋比: WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號(hào): PT0687R
  • 特異性: Endogenous
  • 基因名稱: SMAD1
  • 蛋白名稱: Mothers against decapentaplegic homolog 1
  • 別名: SMAD1;BSP1;MADH1;MADR1;Mothers against decapentaplegic homolog 1;MAD homolog 1;Mothers against DPP homolog 1;JV4-1;Mad-related protein 1;SMAD family member 1;SMAD 1;Smad1;hSMAD1;Transforming growth factor-beta-signaling protein 1;BSP-1
  • Organism-1: Human
  • 基因ID-1: 4086
  • SwissProt-1: Q15797
  • Organism-2: Mouse
  • 基因ID-2: 17125
  • SwissProt-2: P70340
  • Organism-3: Rat
  • SwissProt-3: P97588
  • 背景: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-med
  • 細(xì)胞定位: Cytoplasm . Nucleus . Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4 (PubMed:15647271). Co-localizes with LEMD3 at the nucleus inner membrane (PubMed:15647271). Exported from the nucleus to the cytoplasm when dephosphorylated (By similarity). .
Smad1 Rabbit mAb
Catalog No PRM8634
Product information
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點(diǎn)-Target: Smad1
  • 反應(yīng)性-Reactivity: 人,小鼠,大鼠
  • 應(yīng)用-Applications: WB,IF,IP,ELISA
  • MW(Calculated): 52kD
  • MW(Observed): 52kD
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG,Kappa
  • 偶聯(lián)-Conjugate: Unmodified
  • 推薦稀釋比: WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號(hào): PT0687R
  • 特異性: Endogenous
  • 基因名稱: SMAD1
  • 蛋白名稱: Mothers against decapentaplegic homolog 1
  • 別名: SMAD1;BSP1;MADH1;MADR1;Mothers against decapentaplegic homolog 1;MAD homolog 1;Mothers against DPP homolog 1;JV4-1;Mad-related protein 1;SMAD family member 1;SMAD 1;Smad1;hSMAD1;Transforming growth factor-beta-signaling protein 1;BSP-1
  • Organism-1: Human
  • 基因ID-1: 4086
  • SwissProt-1: Q15797
  • Organism-2: Mouse
  • 基因ID-2: 17125
  • SwissProt-2: P70340
  • Organism-3: Rat
  • SwissProt-3: P97588
  • 背景: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-med
  • 細(xì)胞定位: Cytoplasm . Nucleus . Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4 (PubMed:15647271). Co-localizes with LEMD3 at the nucleus inner membrane (PubMed:15647271). Exported from the nucleus to the cytoplasm when dephosphorylated (By similarity). .
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.hyjdss.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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