儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0860R
特異性： Endogenous
基因名稱： STAT5A
蛋白名稱： Signal transducer and activator of transcription 5A
別名： STAT5A;STAT5;Signal transducer and activator of transcription 5A
Organism-1： Human
基因ID-1： 6776
SwissProt-1： P42229
Organism-2： Mouse
基因ID-2： 20850
SwissProt-2： P42230
Organism-3： Rat
基因ID-3： 24918
SwissProt-3： Q62771
背景： The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0860R
特異性： Endogenous
基因名稱： STAT5A
蛋白名稱： Signal transducer and activator of transcription 5A
別名： STAT5A;STAT5;Signal transducer and activator of transcription 5A
Organism-1： Human
基因ID-1： 6776
SwissProt-1： P42229
Organism-2： Mouse
基因ID-2： 20850
SwissProt-2： P42230
Organism-3： Rat
基因ID-3： 24918
SwissProt-3： Q62771
背景： The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been
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