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CENP-A Rabbit mAb
商品貨號: PRM8103
適 應(yīng) 性: 人,小鼠,大鼠
WB IF ELISA IP
¥800元
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商品描述
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點-Target: CENP-A
  • 反應(yīng)性-Reactivity: 人,小鼠,大鼠
  • 應(yīng)用-Applications: WB,IF,IP,ELISA
  • MW(Calculated): 16kD
  • MW(Observed): 16kD
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG,Kappa
  • 偶聯(lián)-Conjugate: Unmodified
  • 推薦稀釋比: WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性: Monoclonal
  • 克隆號: PT0712R
  • 特異性: Endogenous
  • 基因名稱: CENPA
  • 蛋白名稱: Histone H3-like centromeric protein A
  • 別名: CENPA;Histone H3-like centromeric protein A;Centromere autoantigen A;Centromere protein A;CENP-A
  • Organism-1: Human
  • 基因ID-1: 1058
  • SwissProt-1: P49450
  • Organism-2: Mouse
  • SwissProt-2: O35216
  • 背景: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015],
  • 細胞定位: Nucleus . Chromosome, centromere, kinetochore . Chromosome, centromere . Localizes exclusively in the kinetochore domain of centromeres. Occupies a compact domain at the inner kinetochore plate stretching across 2 thirds of the length of the constriction but encompassing only one third of the constriction width and height (PubMed:19114591). Phosphorylation at Ser-68 during early mitosis abolishes association with chromatin and centromeres and results in dispersed nuclear location (PubMed:25556658). .
CENP-A Rabbit mAb
Catalog No PRM8103
Product information
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點-Target: CENP-A
  • 反應(yīng)性-Reactivity: 人,小鼠,大鼠
  • 應(yīng)用-Applications: WB,IF,IP,ELISA
  • MW(Calculated): 16kD
  • MW(Observed): 16kD
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG,Kappa
  • 偶聯(lián)-Conjugate: Unmodified
  • 推薦稀釋比: WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性: Monoclonal
  • 克隆號: PT0712R
  • 特異性: Endogenous
  • 基因名稱: CENPA
  • 蛋白名稱: Histone H3-like centromeric protein A
  • 別名: CENPA;Histone H3-like centromeric protein A;Centromere autoantigen A;Centromere protein A;CENP-A
  • Organism-1: Human
  • 基因ID-1: 1058
  • SwissProt-1: P49450
  • Organism-2: Mouse
  • SwissProt-2: O35216
  • 背景: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015],
  • 細胞定位: Nucleus . Chromosome, centromere, kinetochore . Chromosome, centromere . Localizes exclusively in the kinetochore domain of centromeres. Occupies a compact domain at the inner kinetochore plate stretching across 2 thirds of the length of the constriction but encompassing only one third of the constriction width and height (PubMed:19114591). Phosphorylation at Ser-68 during early mitosis abolishes association with chromatin and centromeres and results in dispersed nuclear location (PubMed:25556658). .
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.hyjdss.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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