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PRAK Monoclonal Antibody
商品貨號： PLA004997
適 應(yīng) 性： 人
WB IHC IF ELISA
￥600元
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MSDS
說明書
商品描述
  • 發(fā)貨日期： 7
  • 基因名稱： MAPKAPK5
  • 蛋白名稱： MAP kinase-activated protein kinase 5
  • Human_gene_id： 8550
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8550
  • Human_swiss_prot_no： Q8IW41
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/Q8IW41/entry
  • Mouse_swiss_prot_no： O54992
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/O54992
  • 特異性： PRAK Monoclonal Antibody detects endogenous levels of PRAK protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
  • 純化工藝： Affinity purification
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： MAPKAPK5; PRAK; MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5; p38-regulated/activated protein kinase; PRAK
  • 信號通路： MAPK_ERK_Growth;MAPK_G_Protein;
  • 功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:p38 alpha and beta-dependent phosphorylation increases its activity. Activated by stress-related extracellular stimuli; such as H(2)O(2), arsenite, anisomycin TNF alpha and also PMA and the calcium ionophore A23187; but to a lesser extent. In vitro, activated by SQSTM1.,function:Mediates stress-induced small heat shock protein 27 phosphorylation.,PTM:Phosphorylated on Thr-182; which is the regulatory phosphorylation site and is located on the T-loop/loop 12.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:Also observed in the nucleus.,subunit:Interacts with SQSTM1.,tissue specificity:Expressed ubiquitously.,
  • 相關(guān)產(chǎn)品： YT3849,YT3848,YP0820,KA4169C,KA1752C
  • 細胞定位： Cytoplasm. Nucleus. Translocates to the cytoplasm following phosphorylation and activation. Interaction with ERK3/MAPK6 or ERK4/MAPK4 and phosphorylation at Thr-182, activates the protein kinase activity, followed by translocation to the cytoplasm. Phosphorylation by PKA/PRKACA at Ser-115 also induces nuclear export.
  • 組織表達： Expressed ubiquitously.
  • 科研貨號： PLA004997
PRAK Monoclonal Antibody
Catalog No PLA004997
Product information
  • 發(fā)貨日期： 7
  • 基因名稱： MAPKAPK5
  • 蛋白名稱： MAP kinase-activated protein kinase 5
  • Human_gene_id： 8550
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8550
  • Human_swiss_prot_no： Q8IW41
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/Q8IW41/entry
  • Mouse_swiss_prot_no： O54992
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/O54992
  • 特異性： PRAK Monoclonal Antibody detects endogenous levels of PRAK protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
  • 純化工藝： Affinity purification
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： MAPKAPK5; PRAK; MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5; p38-regulated/activated protein kinase; PRAK
  • 信號通路： MAPK_ERK_Growth;MAPK_G_Protein;
  • 功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:p38 alpha and beta-dependent phosphorylation increases its activity. Activated by stress-related extracellular stimuli; such as H(2)O(2), arsenite, anisomycin TNF alpha and also PMA and the calcium ionophore A23187; but to a lesser extent. In vitro, activated by SQSTM1.,function:Mediates stress-induced small heat shock protein 27 phosphorylation.,PTM:Phosphorylated on Thr-182; which is the regulatory phosphorylation site and is located on the T-loop/loop 12.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:Also observed in the nucleus.,subunit:Interacts with SQSTM1.,tissue specificity:Expressed ubiquitously.,
  • 相關(guān)產(chǎn)品： YT3849,YT3848,YP0820,KA4169C,KA1752C
  • 細胞定位： Cytoplasm. Nucleus. Translocates to the cytoplasm following phosphorylation and activation. Interaction with ERK3/MAPK6 or ERK4/MAPK4 and phosphorylation at Thr-182, activates the protein kinase activity, followed by translocation to the cytoplasm. Phosphorylation by PKA/PRKACA at Ser-115 also induces nuclear export.
  • 組織表達： Expressed ubiquitously.
  • 科研貨號： PLA004997
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.hyjdss.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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