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PLZF Monoclonal Antibody
商品貨號: PLA004993
適 應(yīng) 性:
WB IF ELISA
¥600元
規(guī)格:
在線咨詢
MSDS
說明書
商品描述
  • 發(fā)貨日期: 7
  • 基因名稱: ZBTB16
  • 蛋白名稱: Zinc finger and BTB domain-containing protein 16
  • Human_gene_id: 7704
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7704
  • Human_swiss_prot_no: Q05516
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q05516/entry
  • 特異性: PLZF Monoclonal Antibody detects endogenous levels of PLZF protein.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源: Monoclonal, Mouse
  • 稀釋: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝: Affinity purification
  • 儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: ZBTB16; PLZF; ZNF145; Zinc finger and BTB domain-containing protein 16; Promyelocytic leukemia zinc finger protein; Zinc finger protein 145; Zinc finger protein PLZF
  • 信號通路: Pathways in cancer;Acute myeloid leukemia;
  • 功能: disease:A chromosomal aberration involving ZBTB16 may be a cause of acute promyelocytic leukemia (APL). Translocation t(11;17)(q32;q21) with RARA.,disease:Defects in ZBTB16 are the cause of skeletal defects genital hypoplasia and mental retardation [MIM:612447]. The disorder is characterized by mental retardation, craniofacial dysmorphism, microcephaly and short stature. Additional features include absence of the thumbs, hypoplasia of the radii and ulnae, additional vertebrae and ribs, retarded bone age and genital hypoplasia.,function:Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,induction:By retinoic acid.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 9 C2H2-type zinc fingers.,subunit:Binds EPN1. Interacts with ZBTB32 and CUL3.,tissue specificity:Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細胞定位: Nucleus . Nucleus, nuclear body .
  • 組織表達: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.
  • 科研貨號: PLA004993
PLZF Monoclonal Antibody
Catalog No PLA004993
Product information
  • 發(fā)貨日期: 7
  • 基因名稱: ZBTB16
  • 蛋白名稱: Zinc finger and BTB domain-containing protein 16
  • Human_gene_id: 7704
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7704
  • Human_swiss_prot_no: Q05516
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q05516/entry
  • 特異性: PLZF Monoclonal Antibody detects endogenous levels of PLZF protein.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源: Monoclonal, Mouse
  • 稀釋: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝: Affinity purification
  • 儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: ZBTB16; PLZF; ZNF145; Zinc finger and BTB domain-containing protein 16; Promyelocytic leukemia zinc finger protein; Zinc finger protein 145; Zinc finger protein PLZF
  • 信號通路: Pathways in cancer;Acute myeloid leukemia;
  • 功能: disease:A chromosomal aberration involving ZBTB16 may be a cause of acute promyelocytic leukemia (APL). Translocation t(11;17)(q32;q21) with RARA.,disease:Defects in ZBTB16 are the cause of skeletal defects genital hypoplasia and mental retardation [MIM:612447]. The disorder is characterized by mental retardation, craniofacial dysmorphism, microcephaly and short stature. Additional features include absence of the thumbs, hypoplasia of the radii and ulnae, additional vertebrae and ribs, retarded bone age and genital hypoplasia.,function:Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,induction:By retinoic acid.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 9 C2H2-type zinc fingers.,subunit:Binds EPN1. Interacts with ZBTB32 and CUL3.,tissue specificity:Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細胞定位: Nucleus . Nucleus, nuclear body .
  • 組織表達: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.
  • 科研貨號: PLA004993
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.hyjdss.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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