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p57 Monoclonal Antibody
商品貨號(hào): PLA004972
適 應(yīng) 性:
WB ELISA
¥600元
規(guī)格:
在線咨詢
MSDS
說(shuō)明書
商品描述
  • 發(fā)貨日期: 7
  • 基因名稱: CDKN1C
  • 蛋白名稱: Cyclin-dependent kinase inhibitor 1C
  • Human_gene_id: 1028
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1028
  • Human_swiss_prot_no: P49918
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P49918/entry
  • Mouse_swiss_prot_no: P49919
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P49919
  • 特異性: p57 Monoclonal Antibody detects endogenous levels of p57 protein.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源: Monoclonal, Mouse
  • 稀釋: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝: Affinity purification
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2
  • 信號(hào)通路: Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;
  • 功能: disease:Defects in CDKN1C are a cause of Beckwith-Wiedemann syndrome (BWS) [MIM:130650]. BWS is a genetically heterogeneous disorder characterized by anterior abdominal wall defects including exomphalos (omphalocele), pre- and postnatal overgrowth, and macroglossia. Additional less frequent complications include specific developmental defects and a predisposition to embryonal tumors.,disease:Defects in CDKN1C are involved in tumor formation.,function:Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.,similarity:Belongs to the CDI family.,tissue specificity:Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位: Nucleus .
  • 組織表達(dá): Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver.
  • 科研貨號(hào): PLA004972
p57 Monoclonal Antibody
Catalog No PLA004972
Product information
  • 發(fā)貨日期: 7
  • 基因名稱: CDKN1C
  • 蛋白名稱: Cyclin-dependent kinase inhibitor 1C
  • Human_gene_id: 1028
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1028
  • Human_swiss_prot_no: P49918
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P49918/entry
  • Mouse_swiss_prot_no: P49919
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P49919
  • 特異性: p57 Monoclonal Antibody detects endogenous levels of p57 protein.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源: Monoclonal, Mouse
  • 稀釋: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝: Affinity purification
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2
  • 信號(hào)通路: Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;
  • 功能: disease:Defects in CDKN1C are a cause of Beckwith-Wiedemann syndrome (BWS) [MIM:130650]. BWS is a genetically heterogeneous disorder characterized by anterior abdominal wall defects including exomphalos (omphalocele), pre- and postnatal overgrowth, and macroglossia. Additional less frequent complications include specific developmental defects and a predisposition to embryonal tumors.,disease:Defects in CDKN1C are involved in tumor formation.,function:Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.,similarity:Belongs to the CDI family.,tissue specificity:Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位: Nucleus .
  • 組織表達(dá): Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver.
  • 科研貨號(hào): PLA004972
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.hyjdss.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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