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NAC-1 Monoclonal Antibody
商品貨號： PLA004948
適 應(yīng) 性： 人
WB IHC IF ELISA
￥600元
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MSDS
說明書
商品描述
  • 發(fā)貨日期： 7
  • 基因名稱： BTB14
  • 蛋白名稱： Nucleus accumbens-associated protein
  • Human_gene_id： 112939
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=112939
  • Human_swiss_prot_no： Q96RE7
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/Q96RE7/entry
  • Mouse_swiss_prot_no： Q7TSZ8
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/Q7TSZ8
  • 特異性： NAC-1 Monoclonal Antibody detects endogenous levels of NAC-1 protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
  • 純化工藝： Affinity purification
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： NACC1; BTBD14B; NAC1; Nucleus accumbens-associated protein 1; NAC-1; BTB/POZ domain-containing protein 14B
  • 功能： function:Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.,similarity:Contains 1 BTB (POZ) domain.,subcellular location:Distribution in the cytoplasm is dependent on phosphorylation.,subunit:Homooligomer; mediated by the BTB domain. Interacts with HDAC3 and HDAC4. Interacts (via BTB domain) with CUL3, PSMD7 AND RCOR1.,tissue specificity:Overexpressed in several types of carcinomas including ovarian serous carcinomas. Expression levels positively correlate with tumor recurrence in ovarian serous carcinomas, and intense immunoreactivity in primary ovarian tumors predicts early recurrence. Up-regulated in ovarian carcinomas after chemotherapy, suggesting a role in development of chemotherapy resistance in ovarian cancer.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Nucleus. Cytoplasm. Distribution in the cytoplasm is dependent on phosphorylation. .
  • 組織表達(dá)： Overexpressed in several types of carcinomas including ovarian serous carcinomas. Expression levels positively correlate with tumor recurrence in ovarian serous carcinomas, and intense immunoreactivity in primary ovarian tumors predicts early recurrence. Up-regulated in ovarian carcinomas after chemotherapy, suggesting a role in development of chemotherapy resistance in ovarian cancer.
  • 科研貨號： PLA004948
NAC-1 Monoclonal Antibody
Catalog No PLA004948
Product information
  • 發(fā)貨日期： 7
  • 基因名稱： BTB14
  • 蛋白名稱： Nucleus accumbens-associated protein
  • Human_gene_id： 112939
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=112939
  • Human_swiss_prot_no： Q96RE7
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/Q96RE7/entry
  • Mouse_swiss_prot_no： Q7TSZ8
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/Q7TSZ8
  • 特異性： NAC-1 Monoclonal Antibody detects endogenous levels of NAC-1 protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
  • 純化工藝： Affinity purification
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： NACC1; BTBD14B; NAC1; Nucleus accumbens-associated protein 1; NAC-1; BTB/POZ domain-containing protein 14B
  • 功能： function:Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.,similarity:Contains 1 BTB (POZ) domain.,subcellular location:Distribution in the cytoplasm is dependent on phosphorylation.,subunit:Homooligomer; mediated by the BTB domain. Interacts with HDAC3 and HDAC4. Interacts (via BTB domain) with CUL3, PSMD7 AND RCOR1.,tissue specificity:Overexpressed in several types of carcinomas including ovarian serous carcinomas. Expression levels positively correlate with tumor recurrence in ovarian serous carcinomas, and intense immunoreactivity in primary ovarian tumors predicts early recurrence. Up-regulated in ovarian carcinomas after chemotherapy, suggesting a role in development of chemotherapy resistance in ovarian cancer.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Nucleus. Cytoplasm. Distribution in the cytoplasm is dependent on phosphorylation. .
  • 組織表達(dá)： Overexpressed in several types of carcinomas including ovarian serous carcinomas. Expression levels positively correlate with tumor recurrence in ovarian serous carcinomas, and intense immunoreactivity in primary ovarian tumors predicts early recurrence. Up-regulated in ovarian carcinomas after chemotherapy, suggesting a role in development of chemotherapy resistance in ovarian cancer.
  • 科研貨號： PLA004948
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.hyjdss.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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