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Inhibin α Monoclonal Antibody
商品貨號(hào): PLA004881
適 應(yīng) 性: 人,小鼠
WB IF ELISA
¥600元
規(guī)格:
在線(xiàn)咨詢(xún)
MSDS
說(shuō)明書(shū)
商品描述
  • 發(fā)貨日期: 7
  • 基因名稱(chēng): INHA
  • 蛋白名稱(chēng): Inhibin alpha chain
  • Human_gene_id: 3623
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3623
  • Human_swiss_prot_no: P05111
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P05111/entry
  • Mouse_gene_id: 16322
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=16322
  • Mouse_swiss_prot_no: Q04997
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q04997
  • 特異性: Inhibin α Monoclonal Antibody detects endogenous levels of Inhibin α protein.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源: Monoclonal, Mouse
  • 稀釋?zhuān)? WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝: Affinity purification
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū): 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱(chēng): INHA; Inhibin alpha chain
  • 功能: function:Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.,online information:Inhibin entry,PTM:Proteolytic processing yields a number of bioactive forms. The 20/23 kDa forms consist solely of the mature alpha chain, the 26/29 kDa forms consist of the most N-terminal propeptide linked through a disulfide bond to the mature alpha chain, the 50/53 kDa forms encompass the entire proprotein. Each type can be furthermore either mono- or diglycosylated, causing the mass difference.,similarity:Belongs to the TGF-beta family.,subunit:Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.,tissue specificity:Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位: Secreted.
  • 組織表達(dá): Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female.
  • 科研貨號(hào): PLA004881
Inhibin α Monoclonal Antibody
Catalog No PLA004881
Product information
  • 發(fā)貨日期: 7
  • 基因名稱(chēng): INHA
  • 蛋白名稱(chēng): Inhibin alpha chain
  • Human_gene_id: 3623
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3623
  • Human_swiss_prot_no: P05111
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P05111/entry
  • Mouse_gene_id: 16322
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=16322
  • Mouse_swiss_prot_no: Q04997
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q04997
  • 特異性: Inhibin α Monoclonal Antibody detects endogenous levels of Inhibin α protein.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源: Monoclonal, Mouse
  • 稀釋?zhuān)? WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝: Affinity purification
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū): 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱(chēng): INHA; Inhibin alpha chain
  • 功能: function:Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.,online information:Inhibin entry,PTM:Proteolytic processing yields a number of bioactive forms. The 20/23 kDa forms consist solely of the mature alpha chain, the 26/29 kDa forms consist of the most N-terminal propeptide linked through a disulfide bond to the mature alpha chain, the 50/53 kDa forms encompass the entire proprotein. Each type can be furthermore either mono- or diglycosylated, causing the mass difference.,similarity:Belongs to the TGF-beta family.,subunit:Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.,tissue specificity:Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位: Secreted.
  • 組織表達(dá): Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female.
  • 科研貨號(hào): PLA004881
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.hyjdss.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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