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HXK II Monoclonal Antibody
商品貨號： PLA004861
適 應(yīng) 性： 人
WB IHC IF ELISA FCM
￥600元
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商品描述
  • 發(fā)貨日期： 7
  • 基因名稱： HK2
  • 蛋白名稱： Hexokinase-2
  • Human_gene_id： 3099
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3099
  • Human_swiss_prot_no： P52789
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/P52789/entry
  • Mouse_swiss_prot_no： O08528
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/O08528
  • 特異性： HXK II Monoclonal Antibody detects endogenous levels of HXK II protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000.. IF 1:50-200
  • 純化工藝： Affinity purification
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： HK2; Hexokinase-2; Hexokinase type II; HK II; Muscle form hexokinase
  • 信號通路： Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Insulin_Receptor;Type II diabetes mellitus;
  • 功能： catalytic activity:ATP + D-hexose = ADP + D-hexose 6-phosphate.,domain:The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus.,enzyme regulation:Hexokinase is an allosteric enzyme inhibited by its product Glc-6-P.,miscellaneous:In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).,online information:Hexokinase entry,pathway:Carbohydrate metabolism; hexose metabolism.,polymorphism:Although found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.,similarity:Belongs to the hexokinase family.,subcellular location:Its hydrophobic N-terminal sequence may be involved in membrane binding.,subunit:Monomer.,tissue specificity:Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Mitochondrion outer membrane ; Peripheral membrane protein . Cytoplasm, cytosol . The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (PubMed:29298880). The interaction with the mitochondrial outer membrane via the mitochondrial-binding peptide (MBP) region promotes higher stability of the protein (PubMed:29298880). Release from the mitochondrial outer membrane into the cytosol induces permeability transition pore (PTP) opening and apoptosis (PubMed:18350175). .
  • 組織表達(dá)： Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
  • 科研貨號： PLA004861
HXK II Monoclonal Antibody
Catalog No PLA004861
Product information
  • 發(fā)貨日期： 7
  • 基因名稱： HK2
  • 蛋白名稱： Hexokinase-2
  • Human_gene_id： 3099
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3099
  • Human_swiss_prot_no： P52789
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/P52789/entry
  • Mouse_swiss_prot_no： O08528
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/O08528
  • 特異性： HXK II Monoclonal Antibody detects endogenous levels of HXK II protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000.. IF 1:50-200
  • 純化工藝： Affinity purification
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： HK2; Hexokinase-2; Hexokinase type II; HK II; Muscle form hexokinase
  • 信號通路： Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Insulin_Receptor;Type II diabetes mellitus;
  • 功能： catalytic activity:ATP + D-hexose = ADP + D-hexose 6-phosphate.,domain:The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus.,enzyme regulation:Hexokinase is an allosteric enzyme inhibited by its product Glc-6-P.,miscellaneous:In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).,online information:Hexokinase entry,pathway:Carbohydrate metabolism; hexose metabolism.,polymorphism:Although found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.,similarity:Belongs to the hexokinase family.,subcellular location:Its hydrophobic N-terminal sequence may be involved in membrane binding.,subunit:Monomer.,tissue specificity:Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Mitochondrion outer membrane ; Peripheral membrane protein . Cytoplasm, cytosol . The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (PubMed:29298880). The interaction with the mitochondrial outer membrane via the mitochondrial-binding peptide (MBP) region promotes higher stability of the protein (PubMed:29298880). Release from the mitochondrial outer membrane into the cytosol induces permeability transition pore (PTP) opening and apoptosis (PubMed:18350175). .
  • 組織表達(dá)： Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
  • 科研貨號： PLA004861
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.hyjdss.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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