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G6PD Monoclonal Antibody
商品貨號(hào)： PLA004820
適 應(yīng) 性： 人
WB IHC IF ELISA FCM
￥600元
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MSDS
說(shuō)明書(shū)
商品描述
  • 發(fā)貨日期： 7
  • 基因名稱(chēng)： G6PD
  • 蛋白名稱(chēng)： Glucose-6-phosphate 1-dehydrogenase
  • Human_gene_id： 2539
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2539
  • Human_swiss_prot_no： P11413
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/P11413/entry
  • 特異性： G6PD Monoclonal Antibody detects endogenous levels of G6PD protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Monoclonal, Mouse
  • 稀釋?zhuān)? WB 1:500 - 1:2000. IHC 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000.. IF 1:50-200
  • 純化工藝： Affinity purification
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱(chēng)： G6PD; Glucose-6-phosphate 1-dehydrogenase; G6PD
  • 信號(hào)通路： Pentose phosphate pathway;Glutathione metabolism;
  • 功能： catalytic activity:D-glucose 6-phosphate + NADP(+) = D-glucono-1,5-lactone 6-phosphate + NADPH.,disease:Defects in G6PD are the cause of chronic non-spherocytic hemolytic anemia (CNSHA) [MIM:305900]. Deficiency of G6PD is associated with hemolytic anemia in two different situations. First, in areas in which malaria has been endemic, G6PD-deficiency alleles have reached high frequencies (1% to 50%) and deficient individuals, though essentially asymptomatic in the steady state, have a high risk of acute hemolytic attacks. Secondly, sporadic cases of G6PD deficiency occur at a very low frequencies, and they usually present a more severe phenotype. Several types of CNSHA are recognized. Class-I variants are associated with severe NSHA; class-II have an activity <10% of normal; class-III have an activity of 10% to 60% of normal; class-IV have near normal activity.,function:Produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power.,miscellaneous:Has NADP both as cofactor (bound to the N-terminal domain) and as structural element bound to the C-terminal domain.,online information:G6PD deficiency resource,online information:G6PD mutation database,online information:The Singapore human mutation and polymorphism database,pathway:Carbohydrate degradation; pentose phosphate pathway.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.,polymorphism:The sequence shown is that of variant B, the most common variant.,similarity:Belongs to the glucose-6-phosphate dehydrogenase family.,subunit:Homodimer or homotetramer.,tissue specificity:The long isoform is found in lymphoblasts, granulocytes and sperm.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Cytoplasm, cytosol . Membrane; Peripheral membrane protein .
  • 組織表達(dá)： Isoform Long is found in lymphoblasts, granulocytes and sperm.
  • 科研貨號(hào)： PLA004820
G6PD Monoclonal Antibody
Catalog No PLA004820
Product information
  • 發(fā)貨日期： 7
  • 基因名稱(chēng)： G6PD
  • 蛋白名稱(chēng)： Glucose-6-phosphate 1-dehydrogenase
  • Human_gene_id： 2539
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2539
  • Human_swiss_prot_no： P11413
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/P11413/entry
  • 特異性： G6PD Monoclonal Antibody detects endogenous levels of G6PD protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Monoclonal, Mouse
  • 稀釋?zhuān)? WB 1:500 - 1:2000. IHC 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000.. IF 1:50-200
  • 純化工藝： Affinity purification
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱(chēng)： G6PD; Glucose-6-phosphate 1-dehydrogenase; G6PD
  • 信號(hào)通路： Pentose phosphate pathway;Glutathione metabolism;
  • 功能： catalytic activity:D-glucose 6-phosphate + NADP(+) = D-glucono-1,5-lactone 6-phosphate + NADPH.,disease:Defects in G6PD are the cause of chronic non-spherocytic hemolytic anemia (CNSHA) [MIM:305900]. Deficiency of G6PD is associated with hemolytic anemia in two different situations. First, in areas in which malaria has been endemic, G6PD-deficiency alleles have reached high frequencies (1% to 50%) and deficient individuals, though essentially asymptomatic in the steady state, have a high risk of acute hemolytic attacks. Secondly, sporadic cases of G6PD deficiency occur at a very low frequencies, and they usually present a more severe phenotype. Several types of CNSHA are recognized. Class-I variants are associated with severe NSHA; class-II have an activity <10% of normal; class-III have an activity of 10% to 60% of normal; class-IV have near normal activity.,function:Produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power.,miscellaneous:Has NADP both as cofactor (bound to the N-terminal domain) and as structural element bound to the C-terminal domain.,online information:G6PD deficiency resource,online information:G6PD mutation database,online information:The Singapore human mutation and polymorphism database,pathway:Carbohydrate degradation; pentose phosphate pathway.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.,polymorphism:The sequence shown is that of variant B, the most common variant.,similarity:Belongs to the glucose-6-phosphate dehydrogenase family.,subunit:Homodimer or homotetramer.,tissue specificity:The long isoform is found in lymphoblasts, granulocytes and sperm.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Cytoplasm, cytosol . Membrane; Peripheral membrane protein .
  • 組織表達(dá)： Isoform Long is found in lymphoblasts, granulocytes and sperm.
  • 科研貨號(hào)： PLA004820
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.hyjdss.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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